Lumoral® innovation
The European Federation of Periodontology (EFP) recommends both professional and home-based biofilm control for all periodontitis patients. However, traditional photodynamic therapy (aPDT) has until now been limited to clinical use with lasers, making regular treatment both expensive and inaccessible.
Lumoral® changes this by bringing the method into the home with LED technology.
This allows the treatment to be performed safely and regularly, which is essential for achieving a lasting effect. Now, the full potential of aPDT can be utilized in a cost-effective way that supports the patient's daily care.
Interdisciplinary expertise behind
Lumoral® is developed and manufactured by the Finnish company Koite Health, where an expert team of dentists, doctors, engineers, and chemists are behind the technology. The product design is created by Harri Koskinen.
The method is based on interdisciplinary research and solid medical evidence. Both the technology, products, and recommendations are proven effective and developed with a focus on high usability and safety for home use.
Lumoral® is MDR-approved medical device.
The History of Lumoral
2016
The mission of a cardiac surgeon
In 2016, cardiac surgeon Tommi Pätilä performed a complex heart operation at Helsinki University Hospital. Samples from the patient's heart muscle showed that complications were caused by oral bacteria. Pätilä immediately recognized the need for a new approach: he never again wanted to operate on a heart compromised by oral bacteria.
Up to 95% of oral diseases can be attributed to plaque formation. Although mechanical toothbrushing is an effective tool, it removes a maximum of 50–65% of plaque. Dr. Pätilä therefore recognized the necessity of supplementary strategies to target the remaining plaque and reduce the oral bacterial load that can affect both local and systemic health.
The meeting
A significant meeting
Around the same time, Pätilä met Sakari Nikinmaa, a civil engineer working on the Biodesign project at the Children’s Hospital. Nikinmaa was looking for a new, exciting project and was immediately interested in Pätilä’s observations. Together with Nikinmaa and the Biodesign team, they decided to take action. They established a research group at Aalto University, which initiated extensive technical and antibacterial studies.
The team
Important collaboration
The group invited some of the world's leading experts in physics, chemistry, and odontology. World-class expertise was also brought in from the field of technology. Juha Rantala, an internationally recognized semiconductor chemist, joined the team. Rantala has extensive experience in the application of antibacterial blue light. Similarly, the expertise of Saija Perovuo, a laboratory analyst at the Department of Oral and Maxillofacial Diseases, was crucial for the development of Lumoral.
Innovation
Innovation
Extensive trials showed that by combining carefully selected light wavelengths with light-activated mouthwashes, a highly effective but localised antibacterial effect could be achieved. We developed innovative LED components with precisely selected wavelengths. After thousands of in vitro experiments, the parameters were optimised, and we were finally able to present a concrete treatment method: Lumoral, designed by Harri Koskinen.
Clinical trials
The Start
Under the leadership of Professor Timo Sorsa, extensive clinical studies were initiated across Europe. Randomized studies confirmed that the theory holds. When plaque bacteria are regularly inactivated as a supplement to other treatment, current treatment recommendations for periodontitis are significantly improved.
Success
International breakthrough
Lumoral has attracted significant international interest. Lumoral has attracted significant international interest. The treatment targets bacteria in plaque and supports the natural healing of the gums without disturbing the healthy bacterial flora. It enhances daily oral hygiene and supplements ongoing professional treatment, while also helping to prevent future dental problems.
The team continues its scientific work with ongoing studies in academic environments worldwide and has shown that Lumoral can benefit many patient groups with difficult-to-treat oral diseases.
How Lumoral® works
Lumoral® combines four biomodular effects in one effective treatment.
Photobiomodulation (PBM) 810 nm
810 nm light stimulates mitochondria in gum cells and increases their ATP production. This reduces inflammation and promotes tissue healing – a method used clinically, among other things, for treating inflammation of the oral mucosa.
Activated partial thromboplastin time (aPTT)
Indocyanine green binds to bacterial biofilm and is activated by 810 nm light. The energy is converted into heat, which breaks down the biofilm and bacterial cell membranes. The heat exposure also stimulates saliva production.
Photodynamic effect (aPDT)
The same dye also produces a small amount of reactive oxygen species (ROS) when exposed to light, which supports the photothermal effect. This antibacterial effect is also effective in biofilms.
Antibacterial blue light (aBL) 405 nm
Blue light activates bacteria's own porphyrins, which enhances the effect of both aPTT and aPDT treatments. Since the method attacks the bacteria's natural structures, they cannot develop resistance to Lumoral® treatment.
Documented effect
✓ Effective treatment of gingivitis, periodontitis, and peri-implantitis
✓ Can be used regularly without risk of bacterial resistance
✓ Non-invasive and well-tolerated
✓ Reduces plaque and tartar
✓ Reduces inflammation
✓ Reduces periodontal pockets
✓ Promotes long-term oral hygiene
✓ Easy to use, even for the elderly and young people
Benefits for the professional
Lumoral® improves the management of oral inflammation and prepares more patients for treatment.
- Twice the effect: In a 6-month clinical study (n=200), more than twice as many patients achieved healthy gums compared to standard treatment. This allows patients with periodontitis to start, for example, implant or orthodontic treatment sooner.
- Daily control: The treatment works consistently between dental visits, as the biofilm is kept under daily control. This reduces the risk of periodontitis and recurrence of peri-implantitis.
- Targeted support: Lumoral® is ideal for periodontal, implant, and orthodontic patients. For gingivitis or peri-implant mucositis, the effect can be enhanced by using Lumoral® daily as an intensive course.
In practice, this means more predictable treatment, more satisfied patients, and fewer complications.
When inflammation is better managed at home, treatment proceeds more easily, and results become more predictable. This improves the patient experience and reduces costs associated with failed treatments.
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