Lumoral ortho Workflow | Biofilmkontrol ved orthobehandling

Q: 51% with BOP

N = 200 · RANDOMIZED, PEER-REVIEWED · 2026 In Stage I–III periodontitis patients on supportive periodontal care (SPC), reduction in key measurments were greater with home-applied dual-light therapy as an adjunct to SPC than in SPC alone. At 6 months, 51% of participants with the SPC+dual-light had BOP<10%, versus 23% with SPC alone. At 6 months, 63% had visible plaque (VPI) <10% with the SPC+dual-light, versus 38% with SPC alone. The number of sites with PPD ≥4 mm was also lower with SPC+dual-light. Pakarinen S et al. Journal of Periodontology. 2026. DOI: 10.1002/jper.70082

Q: PISA reduction 50,4 %

N = 31 · RANDOMIZED, MULTI-CENTER, PEER-REVIEWED (IN PRESS) · 2026 In a multicenter, Stage I–III periodontitis study on supportive periodontal care (SPC), inflammation and plaque reduction were greater with SPC+home-applied dual-light therapy than with SPC alone. At 6 months, the inflamed periodontal epithelial surface area (PISA), reduced from 385 to 191 mm2 (p=0.034) with the SPC-dual-light, versus 226 to 174 mm2 (p=non-significant). Mean visual plaque index (VPI) reduced from 20,9 to 10,6% with the SPC-dual-light, versus 19,6 to 15,7% with SPC only. Tegelberg P et al. Preprint available at medRxiv. 2025. DOI: 10.1101/2025.03.25.25324596

Q: Plaque reduction -21,2%

N = 30 · CROSSOVER, PEER-REVIEWED · 2025 In a crossover study of healthy adults aged 20–25, when participants were using Lumoral, the Greene-Vermilion plaque scores reduced by 21,2% (significant reduction, p < 0.0001), and 6,5% (p = 0.107) with conventional home-care. This is the closest age profile to many aligner patients. Gusseva L, Lill LL. Journal of Dentistry. 2026. DOI: 10.1016/j.dent.2026.106641

Det ortodontiske apparatmiljø favoriserer plakmodning, inflammatoriske ændringer og demineralisering af emalje mellem besøgene

En klar aligner, der bæres 22 timer om dagen, er ikke en neutral anordning. Ligesom andre ortodontiske anordninger, herunder bøjler og tilbehør, skaber den plaktilbageholdende områder, hvor mundhygiejnen bliver mere krævende. Den forsegler tandoverfladen, reducerer spytrensningen over emaljen og skaber et mikromiljø, hvor plak ophobes ved anordningernes kanter, i cervikale zoner og i mellemrummene mellem tænderne.

Aligners skaber et lukket biofilm-miljø og Brackets er vanskelige at holde helt rene.

22 timers daglig aligner-brug reducerer naturlig spyt clearance og øger risikoen for plak-akkumulering, inflammation og demineralisering mellem kontrolbesøgene.

White spot lesions
Demineralisering omkring aligner-kanter kan kompromittere det æstetiske slutresultat.
Gingival inflammation
Inflammation påvirker væv, komfort og aligner adaptation.
Tracking loss
Inflammeret væv kan reducere tracking accuracy og øge behovet for refinements.
Karies risiko
Acidogene bakterier under aligneren øger risikoen for caries.

Langsigtet risiko

Risikoen ligger i den residuale biofilm

Lumoral adresserer et klinisk vigtigt hul i hygiejnen ved ortodontisk behandling: den resterende biofilm, der forbliver mellem besøg på trods af tandbørstning. Den anvendes som en supplerende hjemmebehandling og er beregnet til at reducere plakophobning, før den udvikler sig til marginal inflammation, syredrevet demineralisering og de vævsændringer, der kan komplicere sporing af aligner og kontrol af ortodontisk behandling.

Lumoral®

Biofilmkontrol designet til daglig brug

Lumoral kombinerer antibakterielt blåt lys med fotodynamisk terapi for at kontrollere plak og inflammatorisk belastning gennem hele aligner-forløbet.

ABL · 405 nm

Målretter plak-associerede bakterier via antibakterielt blåt lys.

APDT · 810 nm + ICG

ICG binder selektivt til plak og aktiveres af nær-infrarødt lys.

Ingen resistens · Ingen staining

Velegnet til kontinuerlig brug gennem hele behandlingsforløbet.

Et alternativ til langvarig chlorhexidine-brug

Problemer med CHX

staining
dysgeusia
microbiome disruption
dårlig compliance

Lumoral®

ingen staining
ingen resistens
ingen microbiome disruption
designet til langtidsbrug
kompatibel med aligners

85% maintained BOP ≤10%

N = 40 · RANDOMIZED · SUBMITTED MANUSCRIPT · DATA ON FILE

In a single-site, randomized, assessor-blinded clinical study of adolescents starting fixed orthodontic treatment, home-applied dual-light aPDT used alongside standard hygiene supported better plaque and inflammation control over 12 weeks than standard hygiene alone. VPI decreased 1.8× more with dual-light aPDT than in controls (-7.65% vs -4.22%). A higher proportion of participants in the dual-light group maintained BOP ≤10% compared with controls (85% vs 58%), and fewer participants showed an increase in BOP values (35.0% vs 78.9%).

Hashemi-Elses et al. ClinicalTrials.gov ID: NCT05825742

51% with BOP<10%

N = 200 · RANDOMIZED, PEER-REVIEWED · 2026

In Stage I–III periodontitis patients on supportive periodontal care (SPC), reduction in key measurments were greater with home-applied dual-light therapy as an adjunct to SPC than in SPC alone. At 6 months, 51% of participants with the SPC+dual-light had BOP<10%, versus 23% with SPC alone. At 6 months, 63% had visible plaque (VPI) <10% with the SPC+dual-light, versus 38% with SPC alone. The number of sites with PPD ≥4 mm was also lower with SPC+dual-light.

Pakarinen S et al. Journal of Periodontology. 2026. DOI: 10.1002/jper.70082

PISA reduction 50,4 %

N = 31 · RANDOMIZED, MULTI-CENTER, PEER-REVIEWED (IN PRESS) · 2026

In a multicenter, Stage I–III periodontitis study on supportive periodontal care (SPC), inflammation and plaque reduction were greater with SPC+home-applied dual-light therapy than with SPC alone. At 6 months, the inflamed periodontal epithelial surface area (PISA), reduced from 385 to 191 mm2 (p=0.034) with the SPC-dual-light, versus 226 to 174 mm2 (p=non-significant). Mean visual plaque index (VPI) reduced from 20,9 to 10,6% with the SPC-dual-light, versus 19,6 to 15,7% with SPC only.

Tegelberg P et al. Preprint available at medRxiv. 2025. DOI: 10.1101/2025.03.25.25324596

Plaque reduction -21,2%

N = 30 · CROSSOVER, PEER-REVIEWED · 2025

In a crossover study of healthy adults aged 20–25, when participants were using Lumoral, the Greene-Vermilion plaque scores reduced by 21,2% (significant reduction, p < 0.0001), and 6,5% (p = 0.107) with conventional home-care. This is the closest age profile to many aligner patients.

Gusseva L, Lill LL. Journal of Dentistry. 2026. DOI: 10.1016/j.dent.2026.106641